IFNAR 1 Recombinant Protein
Product Specifications
Background
Interferon alpha/beta receptor 1 (IFNAR1) is also known as Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1 (CRF2-1), Type I interferon receptor 1, IFNAR, which belongs to the type II cytokine receptor family. IFNAR1 /IFNAR contains four fibronectin type-III domains. IFNAR1 associates with IFNAR2 to form the type I interferon receptor. IFNAR1 is receptor for interferons alpha and beta. IFNAR1 can transduce IFNB signals without the help of IFNAR2, and not activating the Jak-STAT pathway.
CAS Number
9000-83-3
NCBI Gene ID
3454
Swiss Prot
P17181
Accession Number
NP_000620
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Immunology, Signal Transduction
Purity
85% (rh IFNAR1 /IFNAR Fc Chimera) and 13% (Human IgG1 Fc fragment) as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
73.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Interferon (alpha, beta and omega) receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Colamonici O., et al., 1994, Mol. Cell. Biol. 14:8133-8142.
Background Reference 02
Li X., et al., 1997, Mol. Cell. Biol. 17:2048-2056.
Background Reference 03
Russell-Harde D., et al., 1999, Biochem. Biophys. Res. Commun. 255:539-544.
Other Product Names
IFNAR1, IFNAR, CRF2-1, IFN-R-1, IFNAR-1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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