IGFLR1 Recombinant Protein
Product Specifications
Background
Insulin-growth factor-like gene family is a new family of proteins consisting of four proteins in humans (IGFL1 to 4) and one in mice (mIGFL) . mIGFL is expressed in normal skin in mice and further upregulated during inflammation responses in skin or after skin wounding. In human only IGFL1 expression is increased in psoriatic skin samples. mIGFL and human IGFL1 and 3 interact with specificity and high affinity to a novel receptor named IGF-like family receptor 1 (formerly TMEM-149) . Analysis of the amino acid sequence of IGFLR1 indicated that this receptor is likely a novel member of the TNF-R family. IGFLR1 is expressed most abundantly on mouse T cells, suggesting that mIGFL and IGFL1 produced in the skin may potentially exert regulatory functions on T cell responses.
CAS Number
9000-83-3
NCBI Gene ID
79713
Swiss Prot
Q9D6Z6
Accession Number
Q9H665
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Innate Immunity
Concentration
1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 50 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-271
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
IGF-like family receptor 1
NCBI Organism
Homo sapiens
Other Product Names
IGF-like Family Receptor 1, Transmembrane Protein 149, TMEM149, U2 Small Nuclear RNA Auxiliary Factor 1-like 4
Species
Human
Protein ID
13375913
Physical Properties
Lyophilized
Curated Selection
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