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Influenza A Hemagglutinin Recombinant Protein

Product Specifications

Background

Influenza, commonly known as "the flu", is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. The type A viruses are the most virulent human pathogens among the three influenza types and cause the most severe disease. The serotypes that have been confirmed in humans, ordered by the number of known human pandemic deaths, are: H1N1, H2N2, H3N2, H5N1, H7N7, H1N2, H9N2, H7N2, H7N3, H10N7, H7N9. H7N9 is a serotype of the species Influenzavirus A (avian influenza virus or bird flu virus) . H7 normally circulates amongst avian populations with some variants known to occasionally infect humans. An H7N9 virus was first reported to have infected humans in 2013 in China.

CAS Number

9000-83-3

Tag

C-Fc Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Infectious Disease

Purity

>95% as determined by SDS-PAGE.

Buffer

50 mM tris, 100 mM glycine, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

84.5 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

Background Reference 01

Eccles, R., 2005, Lancet Infect Dis 5 (11) : 718–25.

Background Reference 02

Hui DS., 2008, Respirology. 13 Suppl 1: S10–3.

Background Reference 03

Shadbolt, Peter. 2013, CNN. Retrieved 25 April 2013.

Background Reference 04

The fight against bird flu. Nature 496 (7446) : 397. April 24, 2013.

Other Product Names

Influenza A, H7N9, H5N1, HA, Hemagglutinin, influenza (flu) virus, H1N1, H2N2, H3N2, H7N7, H1N2, H7N2, H7N3, H10N7

Tested Applications

WB

Species

Influenza A

Physical Properties

Lyophilized

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