IgG4 Fc Region Recombinant Protein
Product Specifications
Background
Immunoglobulin G4 (IgG4) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-4 chain Fc region contains two constant regions of IgG4 H chain (CH2, CH3) .
CAS Number
9000-83-3
NCBI Gene ID
3503
Swiss Prot
P01861
Accession Number
P01861
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
25.8 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Immunoglobulin heavy constant gamma 4 (G4m marker)
NCBI Organism
Homo sapiens
Background Reference 01
Frangione B., et al., 1969, Nature 221:145-148.
Background Reference 02
Kristiansen T.Z., et al., 2004, Mol. Cell. Proteomics 3:715-728.
Background Reference 03
Chen R., et al., 2009, J. Proteome Res. 8:651-661.
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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