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IgG3 Fc Region Recombinant Protein

Product Specifications

Background

Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3) .

CAS Number

9000-83-3

NCBI Gene ID

3502

Swiss Prot

P01860

Accession Number

P01860

Type

Recombinant Proteins

Source

HEK293 cells

Purity

>95% as determined by SDS-PAGE.

Buffer

Tris with Glycine, Arginine and NaCl, pH7.5

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

31.2 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Immunoglobulin heavy constant gamma 3 (G3m marker)

NCBI Organism

Homo sapiens

Background Reference 01

Huck S., et al., 1986, Nucleic Acids Res. 14:1779-1789.

Background Reference 02

Sikorav J.-L., et al., 1980, Nucleic Acids Res. 8:3143-3155.

Other Product Names

IgG3 Fc, IGHG3

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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