IgG3 Fc Region Recombinant Protein
Product Specifications
Background
Immunoglobulin G3 (IgG3) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F (ab) s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. Ig gamma-3 chain C region (IgG3-Fc / IGHG3) contains two constant regions of IgG3 H chain (CH2, CH3) .
NCBI Gene ID
3502
Swiss Prot
P01860
Accession Number
P01860
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-416
Calculated Molecular Weight
31.2 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Immunoglobulin heavy constant gamma 3 (G3m marker)
NCBI Organism
Homo sapiens
Background Reference 01
Huck S., et al., 1986, Nucleic Acids Res. 14:1779-1789.
Background Reference 02
Sikorav J.-L., et al., 1980, Nucleic Acids Res. 8:3143-3155.
Other Product Names
IgG3 Fc, IGHG3
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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