IL-36 alpha Recombinant Protein
Product Specifications
Background
IL-36alpha (IL-1F6), IL-36beta (IL-1F8) and IL-36gamma (IL-1F9) bind to IL-36R (IL-1Rrp2) and IL-1RAcP, activating similar intracellular signals as IL-1. IL-36Ra inhibits the production of proinflammatory cytokines, including IL-12, IL-1beta, IL-6, TNF-alpha and IL-23 induced by IL-36 in BMDC and CD4 T cells. Skin and dendritic cells are targets of the IL-36 interleukins leading to a Th1 response. These cytokines may represent potential targets for immune-mediated inflammatory conditions or, alternatively, could be used as adjuvants in vaccination.
NCBI Gene ID
54448
Swiss Prot
Q8NAU1
Accession Number
Q9JLA2
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-282
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Interleukin 1 family, member 6
NCBI Organism
Mus musculus
Other Product Names
Interleukin-36alpha, Interleukin-1 Family Member 6, IL-1F6, FIL1epsilon, Interleukin-1epsilon, Interleukin-1 Homolog 1, IL-1H1
Species
Mouse
Protein ID
25008592
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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