IL-1alpha Recombinant Protein (Animal Free)
Product Specifications
Background
IL-1α is a non-secreted, proinflammatory cytokine produced in a variety of cells, including monocytes, tissue macrophages, keratinocytes, and other epithelial cells. Both IL-1α and IL-1β bind to the same receptor and have similar, if not identical, biological properties. These cytokines have a broad range of activities including the stimulation of thymocyte proliferation by inducing IL-2 release, Bcell maturation and proliferation, mitogenic FGF-like activity and the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant Human IL-1α is an 18.0 kDa protein containing 159 amino acid residues.
CAS Number
9000-83-3
NCBI Gene ID
3552
Swiss Prot
P01583
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Neuroscience, Stem Cell, Cancer, Obesity
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Interleukin 1, alpha
NCBI Organism
Homo sapiens
Other Product Names
Hematopoietin-1, Lymphocyte-activating factor (LAF), Endogenous Pyrogen (EP), Leukocyte, Endogenous Mediator (LEM), Mononuclear Cell Factor (MCF)
Species
Human, Mouse
Physical Properties
Lyophilized
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