IL-10 Recombinant Protein (Animal Free)

Product Specifications

Background

IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-α. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Human IL-10 is an 18.6 kDa protein of 161 amino acid residues.

CAS Number

9000-83-3

NCBI Gene ID

3586

Swiss Prot

P22301

Type

Recombinant Proteins

Source

E. coli

Field of Research

Infectious Disease, Immunology, Neuroscience, Stem Cell, Cancer

Purity

≥ 98% by SDS-PAGE gel and HPLC analyses.

Shipping Conditions

Room Temp

Storage Conditions

The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.