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Kallikrein 11 Recombinant Protein

Product Specifications

Background

Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide, a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

CAS Number

9000-83-3

NCBI Gene ID

11012

Swiss Prot

Q9UBX7

Accession Number

Q9UBX7

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Cancer, Signal Transduction

Buffer

Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 2mM CaCl2, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

26.28 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Kallikrein related peptidase 11

NCBI Organism

Homo sapiens

Other Product Names

Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP

Species

Human

Physical Properties

Liquid

Frequently Asked Questions

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