Kallikrein 11 Recombinant Protein
Product Specifications
Background
Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide, a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.
CAS Number
9000-83-3
NCBI Gene ID
11012
Swiss Prot
Q9UBX7
Accession Number
Q9UBX7
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Cancer, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 2mM CaCl2, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
26.28 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Kallikrein related peptidase 11
NCBI Organism
Homo sapiens
Other Product Names
Kallikrein-11, hK11, Hippostasin, Serine Protease 20, Trypsin-Like Protease, KLK11, PRSS20, TLSP
Species
Human
Physical Properties
Liquid
Frequently Asked Questions
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