Histone Chaperone ASF1A Recombinant Protein
Product Specifications
Background
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
NCBI Gene ID
25842
Swiss Prot
Q9Y294
Accession Number
Q9Y294
Tag
C-6 His, N-T7 tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-270
Calculated Molecular Weight
25.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Anti-silencing function 1A histone chaperone
NCBI Organism
Homo sapiens
Other Product Names
Histone Chaperone ASF1A, Anti-Silencing Function Protein 1 Homolog A, hAsf1, hAsf1a, CCG1-Interacting Factor A, CIA, hCIA, ASF1A
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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