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Histone Chaperone ASF1A Recombinant Protein

Product Specifications

Background

Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.

CAS Number

9000-83-3

NCBI Gene ID

25842

Swiss Prot

Q9Y294

Accession Number

Q9Y294

Tag

C-6 His, N-T7 tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Cancer

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

25.4 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Anti-silencing function 1A histone chaperone

NCBI Organism

Homo sapiens

Other Product Names

Histone Chaperone ASF1A, Anti-Silencing Function Protein 1 Homolog A, hAsf1, hAsf1a, CCG1-Interacting Factor A, CIA, hCIA, ASF1A

Species

Human

Physical Properties

Lyophilized

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