Histone Chaperone ASF1A Recombinant Protein
Product Specifications
Background
Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many cells and tissues, interacting with histones H3 and H4. ASF1A cooperates with Chromatin Assembly Factor 1 to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. In addition, ASF1A is necessary for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit.
CAS Number
9000-83-3
NCBI Gene ID
25842
Swiss Prot
Q9Y294
Accession Number
Q9Y294
Tag
C-6 His, N-T7 tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM TrisHCl, 1mM DTT, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
25.4 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Anti-silencing function 1A histone chaperone
NCBI Organism
Homo sapiens
Other Product Names
Histone Chaperone ASF1A, Anti-Silencing Function Protein 1 Homolog A, hAsf1, hAsf1a, CCG1-Interacting Factor A, CIA, hCIA, ASF1A
Species
Human
Physical Properties
Lyophilized
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