CX3CL1 Recombinant Protein
Product Specifications
Background
Human Fractalkine (CX3CL1) is a member of the CX3C family of chemokines. Human Fractalkine contains both chemokine and mucin domain. The soluble form of Fractalkine is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane bound form of Fractalkine promotes leukocytes adhesion to endothelial cells. Fractalkine regulates leukocyte adhesion and migration processes at the endothelium and binds to CX3CR1. Natural Human Fractalkine is produced as a long protein (373-amino acid) . The mucin-like stalk permits it to bind to the cell surface.
CAS Number
9000-83-3
NCBI Gene ID
6376
Swiss Prot
P78423
Accession Number
P78423
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Field of Research
Chemokines & Cytokines, Immunology, Infectious Disease, Innate Immunity
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
34.36 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
C-X3-C motif chemokine ligand 1
NCBI Organism
Homo sapiens
Other Product Names
Fractalkine, C-X3-C Motif Chemokine 1, CX3C Membrane-Anchored Chemokine, Neurotactin, Small-Inducible Cytokine D1, CX3CL1, FKN, NTT, SCYD1
Species
Human
Physical Properties
Lyophilized
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