CCL8 Recombinant Protein

Product Specifications

Background

Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.

CAS Number

9000-83-3

NCBI Gene ID

6355

Swiss Prot

P80075

Accession Number

P80075

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Chemokines & Cytokines

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,1mM EDTA, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

9.95 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

C-C motif chemokine ligand 8

NCBI Organism

Homo sapiens

Other Product Names

C-C Motif Chemokine 8, HC14, Monocyte Chemoattractant Protein 2, Monocyte Chemotactic Protein 2, MCP-2, Small-Inducible Cytokine A8, CCL8, MCP2, SCYA10, SCYA8