CD275 [B7-H2] Recombinant Protein
Product Specifications
Background
Human B7-H2 is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2 and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. Human B7-H2 is expressed constitutively on resting B cells, dendritic cells and at low levels on monocytes. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
CAS Number
9000-83-3
NCBI Gene ID
23308
Swiss Prot
P07750
Accession Number
NP_056074
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute with 100 μ l sterile water. Add 1X PBS to the desired protein concentration.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Inducible T-cell co-stimulator ligand
NCBI Organism
Homo sapiens
Other Product Names
B7-H2, ICOS Ligand, B7-like Protein Gl50, B7RP-1
Species
Human
Protein ID
27477039
Physical Properties
Lyophilized
Curated Selection
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