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High Mobility Group Protein B2 Recombinant Protein

Product Specifications

Background

High Mobility Group Protein B2 (HMGB2) belongs to the non-histone chromosomal high-mobility group protein family. Members of this family are chromatin-associated and widely spread in the nucleus of higher eukaryotic cells. HMGB2 contains 2 HMG box DNA-binding domains. It is associated with chromatin and has the ability to bend DNA, preferentially single-stranded DNA. It is shown that HMGB2 is able to efficiently bend DNA and form DNA circles. In addition, HMGB2 is involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V (D) J recombination.

NCBI Gene ID

3148

Swiss Prot

P26583

Accession Number

P26583

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Field of Research

Other

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl, pH7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=91-711

Calculated Molecular Weight

25.07 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

High mobility group box 2

NCBI Organism

Homo sapiens

Other Product Names

High Mobility Group Protein B2, High Mobility Group Protein 2, HMG-2, HMGB2, HMG2

Species

Human

Protein ID

261385112

Physical Properties

Lyophilized

CAS Number

9000-83-3

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