HPGDS Recombinant Protein

Product Specifications

Background

Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH (2) . HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.

CAS Number

9000-83-3

NCBI Gene ID

27306

Swiss Prot

O60760

Accession Number

O60760

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Buffer

Supplied as a 0.2 um filtered solution of 20mM Tris, 200mM NaCl, pH 7.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

23.6 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Hematopoietic prostaglandin D synthase

NCBI Organism

Homo sapiens

Other Product Names

Hematopoietic Prostaglandin D Synthase, H-PGDS, GST Class-Sigma, Glutathione S-Transferase, Glutathione-Dependent PGD Synthase, Glutathione-Requiring Prostaglandin D Synthase, Prostaglandin-H2 D-Isomerase, HPGDS, GSTS, PGDS, PTGDS2