HSP 90 alpha Recombinant Protein
Product Specifications
Background
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
CAS Number
9000-83-3
NCBI Gene ID
3320
Swiss Prot
P07900
Accession Number
NP_005339
Tag
N-GST Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Obesity, Signal Transduction, Other
Purity
>85% as determined by SDS-PAGE.
Buffer
50 mM HEPES, pH7.0, with 150 mM NaCl
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
49.3 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Heat shock protein 90kDa alpha (cytosolic), class A member 1
NCBI Organism
Homo sapiens
Background Reference 01
Martinez-Ruiz A., et al., 2005, Proc. Natl. Acad. Sci. U.S.A. 102:8525-8530.
Background Reference 02
Forsythe H.L., et al., 2001, J. Biol. Chem. 276:15571-15574.
Background Reference 03
Yang J., et al., 2005, EMBO J. 24:1-10.
Other Product Names
HSP90AA1, HSP90A, HSP 86, HSP86, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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