GH receptor Recombinant Protein
Product Specifications
Background
Growth hormone receptor is a transmembrane receptor for growth hormone (GH) . GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.
CAS Number
9000-83-3
NCBI Gene ID
14600
Swiss Prot
Q3UP14
Accession Number
Q3UP14
Tag
C-Fc tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-595
Calculated Molecular Weight
58.3 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Growth hormone receptor
NCBI Organism
Mus musculus
Other Product Names
Growth hormone receptor, Ghr, Growth Hormone R, GHBP
Species
Mouse
Physical Properties
Lyophilized
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