Granzyme B Recombinant Protein
Product Specifications
Background
Granzyme B (GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
CAS Number
9000-83-3
NCBI Gene ID
14939
Swiss Prot
P04187
Accession Number
P04187
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Supplied as a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Calculated Molecular Weight
26.5 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Granzyme B
NCBI Organism
Mus musculus
Other Product Names
Granzyme B (G, H), CTLA-1, Cytotoxic cell protease 1, CCP1, Fragmentin-2, Gzmb, Ctla1
Species
Mouse
Protein ID
767957252
Physical Properties
Liquid
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