Glypican 1 / GPC1 Recombinant Protein
Product Specifications
Background
Glypican 1 has been shown to interact with SLIT2. This protein is involved in the misfolding of normal prion proteins in the cell membrane to the infectious prion form. Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
CAS Number
9000-83-3
NCBI Gene ID
2817
Swiss Prot
P35052
Accession Number
NP_002072.2
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>85% as determined by SDS-PAGE.
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
58.0 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.0 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Glypican 1
NCBI Organism
Homo sapiens
Background Reference 01
Vermeesch JR, et al. 1995. Genomics. 25:327-9.
Background Reference 02
Ronca F, et al. 2001. J Biol Chem. 276 (31) :29141-7.
Background Reference 03
Taylor DR, et al. 2009. PLoS Pathog. 5 (11) :e1000666.
Other Product Names
Glypican 1, GPC1
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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