GAPDH Recombinant Protein
Product Specifications
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is also known as Peptidyl-cysteine S-nitrosylase GAPDH, which is an enzyme that catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules. GAPDH has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. GAPDH can participate in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Also, GAPDH can modulate the organization and assembly of the cytoskeleton. Furthermore, GAPDH is a component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes.
CAS Number
9000-83-3
NCBI Gene ID
2597
Swiss Prot
P04406
Accession Number
AAH01601
Tag
His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Other
Buffer
50 mM Tris, 150 mM NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
36.9 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Glyceraldehyde-3-phosphate dehydrogenase
NCBI Organism
Homo sapiens
Background Reference 01
Tokunaga K., et al., 1987, Cancer Res. 47:5616-5619.
Background Reference 02
Allen R.W., et al., 1987, J. Biol. Chem. 262:649-653.
Background Reference 03
Jarczowski F., et al., 2009, J. Biol. Chem. 284:766-773.
Other Product Names
GAPDH, GAPD, CDABP0047, OK/SW-cl.12
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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