GITR Recombinant Protein
Product Specifications
Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
CAS Number
9000-83-3
Swiss Prot
Q5M835
Accession Number
Q5M835
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
12.1 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Similar to tumor necrosis factor receptor superfamily, member 18
NCBI Organism
Rattus norvegicus
Background Reference 01
Gurney A.L., et al., 1999, Curr. Biol. 9:215-218.
Background Reference 02
Park MS., et al., 2007, Yonsei Med J 48 (5) : 839-46.
Other Product Names
AITR, GITR, TNFRSF18, CD357
Tested Applications
WB
Species
Rat
Physical Properties
Lyophilized
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