Galectin-9 Recombinant Protein
Product Specifications
Background
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for beta-galactoside sugars, such as N-acetyllactosamine (Galbeta1-3GlcNAc or Galbeta1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
CAS Number
9000-83-3
NCBI Gene ID
3965
Swiss Prot
BAA31542
Accession Number
BAA31542
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
36.6 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Galectin-9 isoform short
NCBI Organism
Homo sapiens
Background Reference 01
Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422.
Background Reference 02
Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.
Other Product Names
Galectin-9, LGALS9, Ecalectin
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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