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Galectin-9 Recombinant Protein

Product Specifications

Background

Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for beta-galactoside sugars, such as N-acetyllactosamine (Galbeta1-3GlcNAc or Galbeta1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

CAS Number

9000-83-3

NCBI Gene ID

3965

Swiss Prot

BAA31542

Accession Number

BAA31542

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Immunology

Buffer

20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

36.6 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

Galectin-9 isoform short

NCBI Organism

Homo sapiens

Background Reference 01

Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422.

Background Reference 02

Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.

Other Product Names

Galectin-9, LGALS9, Ecalectin

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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