Frizzled 7 Recombinant Protein
Product Specifications
Background
Frizzled-7 (FZD7) is also known as FzE3, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD7 contains one FZ (frizzled) domain. FZD7 is receptor for Wnt proteins. FZD7 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD7 interacts with MAGI3 and DVL1.
NCBI Gene ID
8324
Swiss Prot
O75084
Accession Number
AAH15915
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Cancer, Growth Factors, Signal Transduction
Purity
>92% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-335
Calculated Molecular Weight
43.3 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Frizzled class receptor 7
NCBI Organism
Homo sapiens
Background Reference 01
Sagara N., et al., 1998, Biochem. Biophys. Res. Commun. 252:117-122.
Other Product Names
FZD7, Frizzled-7, FzE3, Fz-7, hFz7
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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