CX3CL1 Recombinant Protein
Product Specifications
Background
Fractalkine is also known as C-X3-C motif chemokine 1 (CX3CL1) and neurotactin. Fractalkine is a large cytokine protein of 373 amino acids, it contains multiple domains and is the only known member of the CX3C chemokine family. Fractalkine is found commonly throughout the brain, particularly in neural cells, and its receptor is known to be present on microglial cells. It has also been found to be essential for microglial cell migration. CX3CL1 is also up-regulated in the hippocampus during a brief temporal window following spatial learning, the purpose of which may be to regulate glutamate-mediated neurotransmission tone. This indicates a possible role for the chemokine in the protective plasticity process of synaptic scaling.
NCBI Gene ID
6376
Swiss Prot
P78423
Accession Number
AAH01163
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Chemokines & Cytokines, Growth Factors
Buffer
PBS, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-859
Calculated Molecular Weight
35.5 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Chemokine (C-X3-C motif) ligand 1
NCBI Organism
Homo sapiens
Background Reference 01
Bazan J.F., et al., 1997, Nature 385:640-644.
Background Reference 02
Hoover D.M., et al., 2000, J. Biol. Chem. 275:23187-23193.
Other Product Names
CX3CL1, Fractalkine
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
