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Follistatin-like 1 Recombinant Protein

Product Specifications

Background

Follistatin-like 1 (FSTL1) is a secreted glycoprotein that has been grouped into the follistatin family of proteins. FSTL1 is composed of a follistatin domain and two non-functional calcium-binding motifs. It was originally cloned as a TGF beta 1 inducible factor but subsequently shown to regulate diverse developmental pathways and tissue homeostasis. Ablation of the FSTL1 gene in the mouse results in several structural developmental defects and neonatal lethality due to respiratory failure. FSTL1 suppresses BMP signaling, but the precise mechanism of its action has not been elucidated. FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.

NCBI Gene ID

14314

Swiss Prot

Q62356

Accession Number

Q62356

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-648

Calculated Molecular Weight

33.5 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Follistatin-like 1

NCBI Organism

Mus musculus

Other Product Names

Follistatin-related protein 1, Follistatin-like protein 1, TGF-beta-inducible protein TSC-36, Fstl1

Species

Mouse

Physical Properties

Lyophilized

CAS Number

9000-83-3

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