Fetuin B Recombinant Protein
Product Specifications
Background
Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity) . As a liver-derived plasma protein, FETUB is essential for fertilization.
CAS Number
9000-83-3
NCBI Gene ID
26998
Swiss Prot
Q9UGM5
Accession Number
AAH69670
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Neuroscience
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM Tris, 150 mM NaCl, pH8.0
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
42.4 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Fetuin B
NCBI Organism
Homo sapiens
Background Reference 01
Olivier E., et al., 2000, Biochem. J. 350:589-597.
Background Reference 02
Dietzel E., et al., 2013, Dev. Cell 25:106-112.
Background Reference 03
Muzny D.M., et al., 2006, Nature 440:1194-1198.
Other Product Names
FETUB, Fetuin-B, 16G2, Gugu
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
Curated Selection
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