EPO non-lytic Recombinant Protein
Product Specifications
Background
Erythropoietin is the principal hormone involved in the regulation of erythropoiesis by stimulating the proliferation and differentiation of erythroid progenitor cells and the maintenance of a physiological level of circulating erythrocyte mass. It is a glycoprotein produced primarily by the kidney. The biological effects of EPO are mediated by the erythropoietin receptor (Epo R) . Genetic variations in EPO is associated with susceptibility to microvascular complications of diabetes type 2 (MVCD2) (including diabetic retinopathy, diabetic nephropathy leading to end-stage renal disease and diabetic neuropathy) . It is used for the treatment of anemia and misused as a performance-enhancing drug in endurance athletes.
NCBI Gene ID
2056
Swiss Prot
P40933
Accession Number
NP_000790
Tag
Fc Tag
Type
Recombinant Proteins
Source
CHO cells
Field of Research
Cancer, Cell Cycle, Obesity, Signal Transduction
Buffer
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μ g/ml in sterile PBS.
Shipping Conditions
Room Temp
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=90-456
Applications Notes
This recombinant proteins is for research use only.
NCBI Official Name
Erythropoietin
NCBI Organism
Homo sapiens
Other Product Names
Erythropoietin, Epoetin
Species
Human
Protein ID
62240997
Physical Properties
Lyophilized
CAS Number
9000-83-3
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