Ephrin A1 Recombinant Protein
Product Specifications
Background
Ephrin-A1 (EFNA1) is also known as EPLG1, LERK1, TNFAIP4, Immediate early response protein B61, which belongs to the ephrin family. EFNA1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA1 is cell surface GPI-bound ligand for Eph receptors, and is a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA1 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA1 plays an important role in angiogenesis and tumor neovascularization.
NCBI Gene ID
1942
Swiss Prot
P20827
Accession Number
NP_004419
Tag
C-Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Neuroscience, Signal Transduction
Purity
>95% as determined by SDS-PAGE.
Buffer
50 mM tris, 100 mM glycine, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-256
Calculated Molecular Weight
46 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Ephrin-A1
NCBI Organism
Homo sapiens
Background Reference 01
Liu D.-P., et al., 2007, Int. J. Oncol. 30:865-871.
Background Reference 02
Wykosky J., et al., 2008, Oncogene 27:7260-7273.
Other Product Names
EFNA1, Ephrin-A1, LERK-1, TNFAIP4, EPLG1, B61, ECKLG, EFL1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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