Eotaxin Recombinant Protein
Product Specifications
Background
Eotaxin is a CC chemokine that signals through the CCR3 receptor. It is produced by IFN-γ-stimulated endothelial cells and TNF-activated monocytes. Eotaxin selectively chemoattracts eosinophils and, along with Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung and in allergic reactions. Recombinant Murine Eotaxin is an 8.4 kDa protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
CAS Number
9000-83-3
NCBI Gene ID
20292
Swiss Prot
P48298
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Neuroscience
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Chemokine (C-C motif) ligand 11
NCBI Organism
Mus musculus
Other Product Names
CCL11
Species
Human, Mouse, Rat
Physical Properties
Lyophilized
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