Leptin Recombinant Protein (Animal Free)
Product Specifications
Background
Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant Human Leptin is a 16.0 kDa protein containing 147 amino acid residues.
CAS Number
9000-83-3
NCBI Gene ID
3952
Swiss Prot
P41159
Type
Recombinant Proteins
Source
E. coli
Field of Research
Immunology, Neuroscience, Apoptosis, Obesity
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Shipping Conditions
Room Temp
Storage Conditions
The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Leptin
NCBI Organism
Homo sapiens
Other Product Names
Obesity protein (OB)
Species
Human
Physical Properties
Lyophilized
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