Elafin Recombinant Protein
Product Specifications
Background
Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.
NCBI Gene ID
5266
Swiss Prot
P19957
Accession Number
P19957
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-748
Calculated Molecular Weight
11 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Peptidase inhibitor 3
NCBI Organism
Homo sapiens
Other Product Names
Elafin, Elastase-Specific Inhibitor, ESI, Peptidase Inhibitor 3, PI-3, Protease inhibitor WAP3, Skin-Derived Antileukoproteinase, SKALP, WAP Four-Disulfide Core Domain Protein 14, PI3, WAP3, WFDC14, Trappin-2
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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