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CD69 Recombinant Protein

Product Specifications

Background

Early activation antigen CD69 is also known as C-type lectin domain family 2 member C (CLEC2C), Activation inducer molecule (AIM), Early T-cell activation antigen p60, Leukocyte surface antigen Leu-23. CD69 contains one C-type lectin domain. CD69 / CLEC2C is expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets. CD69 is induced by antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes and by interaction of IL-2 with the p75 IL-2R on the surface of NK cells. CD69 / CLEC2C involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

CAS Number

9000-83-3

NCBI Gene ID

969

Swiss Prot

Q07108

Accession Number

AAH07037

Tag

His Tag

Type

Recombinant Proteins

Source

HEK293 cells

Field of Research

Immunology, Signal Transduction

Purity

>95% as determined by SDS-PAGE.

Buffer

PBS, pH7.4

Shipping Conditions

Room Temp

Storage Conditions

Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

Calculated Molecular Weight

16.8 kDa

Applications Notes

This recombinant protein can be used for WB. For research use only.

NCBI Official Name

CD69 molecule

NCBI Organism

Homo sapiens

Background Reference 01

Natarajan K., et al., 2000, Biochemistry 39:14779-14786.

Background Reference 02

Llera A.S., et al., 2001, J. Biol. Chem. 276:7312-7319.

Background Reference 03

Vanek O., et al., 2008, FEBS J. 275:5589-5606.

Other Product Names

CD69, CLEC2C, AIM, BL-AC/P26, EA1, GP32/28, MLR-3

Tested Applications

WB

Species

Human

Physical Properties

Lyophilized

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