DNAM-1 Recombinant Protein
Product Specifications
Background
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
NCBI Gene ID
10666
Swiss Prot
Q15762-1
Accession Number
NP_006557
Tag
Fc Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Immunology
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-864
Calculated Molecular Weight
52.6 kDa
Applications Notes
This recombinant protein can be used for E, WB. For research use only.
NCBI Official Name
CD226 antigen isoform a precursor
NCBI Organism
Homo sapiens
Background Reference 01
Shibuya A., et al.,1995, Immunity 4:573-581.
Background Reference 02
Tahara-Hanaoka S., et al .,2003, Int. Immunol. 16:533-538.
Background Reference 03
Pende D., et al.,2004, Mol. Immunol. 42:463-469.
Other Product Names
DNAM1, CD226, PTA1
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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