DLL3 Recombinant Protein
Product Specifications
Background
Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands.May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 protein is expressed on the surface of tumor cells but not in normal adult tissues.
NCBI Gene ID
10683
Swiss Prot
Q9NYJ7
Accession Number
NP_058637.1
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Other
Purity
>95% as determined by SDS-PAGE.
Buffer
PBS with Arginine, pH7.4
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-349
Calculated Molecular Weight
50.4 kDa
Applications Notes
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.4 kDa. The protein migrates as 50-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
Delta like canonical Notch ligand 3
NCBI Organism
Homo sapiens
Background Reference 01
Tanaka K., et al. 2018, Lung Cancer., 115, 116-120.
Background Reference 02
Laura R. Saunders., et al. 2015, Sci Transl Med., 26, 7 (302) .
Background Reference 03
Zhang J., et al. 2017, Oncol Lett., 13 (6), 4533-4539.
Other Product Names
Delta3, delta-like 3 (Drosophila), delta-like protein 3, DLL3, Pudgy, SCDO1, SCDO1delta3
Tested Applications
ELISA, WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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