DLL1 Recombinant Protein
Product Specifications
Background
Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
NCBI Gene ID
28514
Swiss Prot
O00548
Accession Number
NP_005609
Tag
His Tag
Type
Recombinant Proteins
Source
HEK293 cells
Field of Research
Other
Buffer
50 mM Tris, 150 mM NaCl, pH 7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=96-862
Calculated Molecular Weight
58.4 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Delta-like protein 1 precursor
NCBI Organism
Homo sapiens
Background Reference 01
Han W., et al., 1999, Blood 95:1616-1625.
Background Reference 02
Gray G.E., et al., 1998, Am. J. Pathol. 154:785-794
Background Reference 03
Clark H.F., et al., 2002, Genome Res. 13:2265-2270.
Other Product Names
DLL1, Delta1, H-Delta-1
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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