Beta-Defensin 4 Recombinant Protein

Defensins are cationic peptides. It is an important ingredient of the innate immune system. beta -defensins are expressed on some leukocytes and epithelial surfaces. Four human beta -Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. beta -defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. beta -defensins are also chemoattractant towards immature dendritic cells and memory T cells. The beta -defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence.

Lyophilized from a 0.2 um filtered solution of 20mM PB, 130mM NaCl, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.