Decorin Recombinant Protein
Product Specifications
Background
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane and calcium homeostasis, keratinocyte function, and suppression of angiogenesis. Most recently, soluble decorin has been shown to induce autophagy in endothelial cells and mitophagy in breast carcinoma cells.
NCBI Gene ID
13179
Swiss Prot
P28654
Accession Number
P28654
Tag
C-6 His tag
Type
Recombinant Proteins
Source
Human Cells
Buffer
Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-678
Calculated Molecular Weight
39 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Decorin
NCBI Organism
Mus musculus
Other Product Names
Decorin, Bone proteoglycan II, PG-S2, PG40, Dcn, PGS2, PG40
Species
Mouse
Physical Properties
Lyophilized
CAS Number
9000-83-3
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