Autophagy protein 4C Recombinant Protein
Product Specifications
Background
Cysteine Protease ATG4C (ATG4C) belongs to the peptidase C54 family. It is required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form which is considered to be the phosphatidylethanolamine (PE) -conjugated form, and has the capacity for the binding to autophagosomes. ATG4C is a cytoplasmic protein and high expressed in skeletal muscle, liver, testis and heart. ATG4C can be inhibited by N-ethylmaleimide.
NCBI Gene ID
84938
Swiss Prot
Q96DT6
Accession Number
Q96DT6
Tag
C-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Autophagy
Buffer
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 100mM NaCl, 10% Glycerol, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-044
Calculated Molecular Weight
53.56 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Autophagy related 4C cysteine peptidase
NCBI Organism
Homo sapiens
Other Product Names
Cysteine Protease ATG4C, AUT-Like 3 Cysteine Endopeptidase, Autophagin-3, Autophagy-Related Cysteine Endopeptidase 3, Autophagy-Related Protein 4 homolog C, ATG4C, APG4C, AUTL1, AUTL3
Species
Human
Protein ID
530363504
Physical Properties
Liquid
CAS Number
9000-83-3
Curated Selection
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