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Cystathionine Gamma-Lyase Recombinant Protein

Product Specifications

Background

Cystathionine Gamma-Lyase (CTH) belongs to the trans-sulfuration enzymes family. CTH exists as a homotetramer and interacts with CALM in a calcium-dependent manner. CTH breaks down cystathionine into cysteine, ammonia and 2-oxobutanoate. CTH catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine and has broad substrate specificity. Defects in CTH will lead to cystathioninuria, which is an autosomal recessive phenotype characterized by abnormal accumulation of plasma cystathionine.

CAS Number

9000-83-3

NCBI Gene ID

1491

Swiss Prot

P32929

Accession Number

P32929

Tag

Tag Free

Type

Recombinant Proteins

Source

E. coli

Buffer

Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,20% Glycerol, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.

Shipping Conditions

Dry Ice

Calculated Molecular Weight

44.7 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Cystathionine gamma-lyase

NCBI Organism

Homo sapiens

Other Product Names

Cystathionine Gamma-Lyase, Cysteine-Protein Sulfhydrase, Gamma-Cystathionase, CTH

Species

Human

Physical Properties

Liquid

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