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Cathepsin D Recombinant Protein

Product Specifications

Background

CTSD localizes to the lysosome and consists of a light chain and a heavy chain. CTSD is expressed in epithelial cells as well as in macrophages.CTSD is a lysosomal aspartyl protease that depends critically on protonation of its active site Asp residue and gets activated at pH 5 in endosome of hepatocytes. It has been suggested to facilitate cancer cell migration and invasion by digesting the basement membrane, extracellular matrix and xonnective tissue. In addition, CTSD has been used as a breast cancer tumor marker.

CAS Number

9000-83-3

NCBI Gene ID

13033

Swiss Prot

P18242

Accession Number

P18242

Tag

C-6 His tag

Type

Recombinant Proteins

Source

Human Cells

Buffer

Lyophilized from a 0.2 um filtered solution of 20mM MES,150mM NaCl, pH5.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.

Shipping Conditions

Room Temp

Calculated Molecular Weight

43.9 kD

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Cathepsin D

NCBI Organism

Mus musculus

Other Product Names

Cathepsin D, CTSD, CPSD, CSTD

Species

Mouse

Protein ID

325652083

Physical Properties

Lyophilized

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