Casein kinase I gamma-2 Recombinant Protein
Product Specifications
Background
CSNK1G2 is a cytoplasmic protein which contains one protein kinase domain. It is amember of the CK1 Ser/Thr protein kinase family of the large casein kinase I (CKI) subfamily. CSNK1G2 participates in Wnt signaling, involves in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. It regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses.
NCBI Gene ID
1455
Swiss Prot
P78368
Accession Number
P78368
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cancer, Obesity, Signal Transduction
Buffer
Supplied as a 0.2 um filtered solution of 20mM Tris,500mM NaCl,10%Glycerol,1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Shipping Conditions
Dry Ice
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-197
Calculated Molecular Weight
47.6 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Casein kinase 1 gamma 2
NCBI Organism
Homo sapiens
Other Product Names
Casein kinase I isoform gamma-2, CK1G2, CSNK1G2
Species
Human
Physical Properties
Liquid
CAS Number
9000-83-3
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