IgG1 Fc Recombinant Protein
Product Specifications
Background
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport) . IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
CAS Number
9000-83-3
NCBI Gene ID
3500
Swiss Prot
P01857
Accession Number
AAC82527.1
Tag
Tag free
Type
Recombinant Proteins
Source
HEK293 cells
Purity
>95% as determined by SDS-PAGE.
Buffer
Tris with Glycine, Arginine and NaCl, pH7.5
Shipping Conditions
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Calculated Molecular Weight
26 kDa
Applications Notes
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
Immunoglobulin heavy constant gamma 1
NCBI Organism
Homo sapiens
Background Reference 01
Medinger M, Tzankov A, et al. (2010), J Clin Immunol. 30 Suppl 1:S9-14.
Tested Applications
WB
Species
Human
Physical Properties
Lyophilized
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