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SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant Protein

Product Specifications

Background

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

NCBI Gene ID

43740575

Swiss Prot

QHD43423.2

Accession Number

QHD43423.2

Tag

N-6His tag

Type

Recombinant Proteins

Source

E. coli

Field of Research

Infectious Disease, COVID-19

Purity

Greater than 95% as determined by reducing SDS-PAGE.

Buffer

Supplied as a 0.2 uM filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1mM EDTA, pH 8.0.

Shipping Conditions

Blue Ice

Storage Conditions

Reconstituted protein solution should be store below -20˚ C.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=92-728

Calculated Molecular Weight

49.4kDa, 50-60kDa

Applications Notes

This recombinant protein can be used for biological assays. For research use only.

NCBI Official Name

Nucleocapsid phosphoprotein

NCBI Organism

Severe acute respiratory syndrome coronavirus 2

Other Product Names

2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein

Species

SARS-CoV-2 (COVID-19, 2019-nCoV) Nucleocapsid protein

Physical Properties

Liquid

CAS Number

9000-83-3

Curated Selection

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