SARS-CoV-2 (COVID-19) Nucleocapsid Recombinant Protein
Product Specifications
Background
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
CAS Number
9000-83-3
NCBI Gene ID
43740575
Swiss Prot
QHD43423.2
Accession Number
QHD43423.2
Tag
N-6His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Infectious Disease, COVID-19
Purity
Greater than 95% as determined by reducing SDS-PAGE.
Buffer
Supplied as a 0.2 uM filtered solution of 20 mM Tris-HCl, 300 mM NaCl, 1mM EDTA, pH 8.0.
Shipping Conditions
Blue Ice
Storage Conditions
Reconstituted protein solution should be store below -20˚ C.
Calculated Molecular Weight
49.4kDa, 50-60kDa
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Nucleocapsid phosphoprotein
NCBI Organism
Severe acute respiratory syndrome coronavirus 2
Other Product Names
2019-nCoV coronavirus NP Protein; 2019-nCoV np Protein; 2019-nCoV novel coronavirus Nucleoprotein Protein
Species
SARS-CoV-2 (COVID-19, 2019-nCoV) Nucleocapsid protein
Physical Properties
Liquid
Curated Selection
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