SARS-CoV-2 (COVID-19) S + M + E Recombinant Protein
Product Specifications
Background
Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Accession Number
S (QHD43416.1) &M (QHD43419.1) &E (QHD43418.1)
Tag
N-His Tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Infectious Disease, COVID-19
Purity
>90% as determined by SDS-PAGE
Buffer
Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.
Shipping Conditions
Room Temp
Storage Conditions
Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 ˚ C for one week .Store at -20 to -80 ˚ C for twelve months from the date of receipt.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=11-071
Calculated Molecular Weight
45.56kDa
Applications Notes
Immunogen
Other Product Names
Spike glycoprotein, Membrane protein, Envelope small membrane protein, E protein
Species
SARS-CoV-2
Physical Properties
Lyophilized
CAS Number
9000-83-3
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