Toxin B Recombinant Protein
Product Specifications
Background
Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. Cholera enterotoxin subunit B (CTXB) pentameric ring directs the A subunit to its target by binding to the GM1 gangliosides present on the surface of the intestinal epithelial cells. It can bind five GM1 gangliosides. It has no toxic activity by itself.
CAS Number
9000-83-3
NCBI Gene ID
2613962
Swiss Prot
P01556
Accession Number
P01556
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Buffer
Lyophilized from a 0.2 um filtered solution of 50mM Tris, 200uM NaCl, pH8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Calculated Molecular Weight
11.8 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Cholera enterotoxin subunit B
NCBI Organism
Vibrio cholerae O1 biovar El Tor str. N16961
Other Product Names
Cholera enterotoxin subunit B, Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB, REF: C1001
Species
Vibriocholerae
Physical Properties
Lyophilized
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