CLIC1 Recombinant Protein
Product Specifications
Background
Chloride Intracellular Channel Protein 1 (CLIC1) belongs to the Chloride Channel CLIC family and contains one GST C-terminal domain. CLIC1 can be expressed in various cell types, but it is especially prominent in the heart, placenta, liver, kidney, and pancreas. CLIC1 can insert into membranes and form chloride ion channels. The channel activity depends on the pH. CLIC1 membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. CLIC1 is also involved in the regulation of the cell cycle.
NCBI Gene ID
1192
Swiss Prot
O00299
Accession Number
O00299
Tag
N-6 His tag
Type
Recombinant Proteins
Source
E. coli
Field of Research
Obesity, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM Tris, 150mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=92-150
Calculated Molecular Weight
29 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
Chloride intracellular channel 1
NCBI Organism
Homo sapiens
Other Product Names
Chloride Intracellular Channel Protein 1, Chloride Channel ABP, Nuclear Chloride Ion Channel 27, NCC27, Regulatory Nuclear Chloride Ion Channel Protein, hRNCC, CLIC1, G6
Species
Human
Physical Properties
Lyophilized
CAS Number
9000-83-3
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