CCL1 Recombinant Protein
Product Specifications
Background
Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines. CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell fusion and virus infection.
NCBI Gene ID
6346
Swiss Prot
P22362
Accession Number
P22362
Tag
Tag Free
Type
Recombinant Proteins
Source
E. coli
Field of Research
Chemokines & Cytokines
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.2. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Shipping Conditions
Room Temp
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=91-077
Calculated Molecular Weight
8.62 kD
Applications Notes
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
C-C motif chemokine ligand 1
NCBI Organism
Homo sapiens
Other Product Names
C-C Motif Chemokine 1, Small-Inducible Cytokine A1, T Lymphocyte-Secreted Protein I-309, CCL1, SCYA1, I-309, TCA-3
Species
Human
Protein ID
578877726
Physical Properties
Lyophilized
CAS Number
9000-83-3
Curated Selection
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